Wrist pain from long hours of mouse use is caused by repetitive strain, poor positioning, and constant pressure on the nerves and tendons. Over time, this can lead to inflammation, discomfort, and conditions like carpal tunnel syndrome or tendonitis.

Sitting for long hours with poor posture compresses the spine and puts pressure on the sciatic nerve, leading to back pain or sciatica.

Prolonged screen use causes eye strain due to blue light exposure, reduced blinking, and constant focus. Glare, poor lighting, and improper settings can make it worse.